CBR1 antibody (AA 1-277)

Catalog No. ABIN5775915

This Mouse Monoclonal antibody specifically detects CBR1 in WB, ELISA, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for CBR1 antibody (AA 1-277) (ABIN5775915)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT4E12

Product Details anti-CBR1 Antibody

Binding Specificity: AA 1-277

Purpose: Human Carbonyl reductase 1/CBR1 antibody

Purification: Purified

Immunogen: Recombinant human CBR1 (1-277 aa ) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: Carbonyl reductase 1/CBR1

Background: Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).

NCBI Accession: NP_001748